Lufthansa is selling cheap flights from Madrid, Spain to San Francisco, United States for as low as €271 return! That works out to a cost of just 2.7 (Euro) Cents Per Mile for this 10100 mile journey.

The fare only includes carry-on luggage, so you need to pay extra if you want to check bags.

Our data shows the lowest prices are available in March 2022. See the link(s) below for dates and prices.

Sample date(s) with Skyscanner.com booking link

Sep 4 – Sep 26 (€276)


Sep 6 – Sep 23 (€426)


Sep 8 – Sep 23 (€426)


Sep 8 – Sep 27 (€276)


Sep 9 – Sep 23 (€420)


Sep 22 – Sep 30 (€415)


Dec 17 – Dec 27 (€428)


Mar 2 – Mar 22 (€271)


Mar 2 – Mar 23 (€271)


Mar 2 – Mar 24 (€271)

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We post many cheap flights like this one from Madrid, Spain to San Francisco, United States every single day, so have a look at our Travel Deals page, or check out the related posts below!

Note: Prices are valid at the time of publishing this post, but may change in the future.

COVID-19 Note: During these uncertain times, please make sure to check the relevant Coronavirus restrictions for your destination before you book and before you fly. We recommend also checking the refund policy of the airline, as well as purchasing travel insurance for your trip.