TAP Air Portugal is selling cheap flights from Madrid, Spain to San Francisco, United States for as low as €252 return! That works out to a cost of just 2.5 (Euro) Cents Per Mile for this 10100 mile journey.

The fare only includes carry-on luggage, so you need to pay extra if you want to check bags.

Our data shows the lowest prices are available in April 2022. See the link(s) below for dates and prices.

Sample date(s) with Kiwi.com booking link

Jan 10 – Jan 20 (€280)

Jan 15 – Jan 22 (€280)

Jan 17 – Jan 23 (€280)

Feb 1 – Feb 6 (€280)

Feb 21 – Feb 28 (€280)

Mar 17 – Mar 28 (€280)

Apr 3 – Apr 10 (€252)

Apr 8 – Apr 17 (€252)

Apr 15 – Apr 24 (€252)

Apr 21 – Apr 25 (€280)

Are you looking for an apartment to rent for your stay in San Francisco, United States? Check out what Vrbo.com has to offer!

We post many cheap flights like this one from Madrid, Spain to San Francisco, United States every single day, so have a look at our Travel Deals page, or check out the related posts below!

Note: Prices are valid at the time of publishing this post, but may change in the future.

COVID-19 Note: During these uncertain times, please make sure to check the relevant Coronavirus restrictions for your destination before you book and before you fly. We recommend also checking the refund policy of the airline, as well as purchasing travel insurance for your trip.